Melanotan II 10mg – tan and libido

This peptide stimulates darkening of the skin and affects appetite and sexual behavior, mimicking natural signals in the body that regulate pigmentation and some brain functions.

What is Melanotan II ?

As a melanocortin agonist, the substance activates receptors from the melanocortin receptors family (MC1R–MC5R), which are GPCRs and signal primarily through Gs → adenylate cyclase → cAMP → PKA cascade, with subsequent changes in transcription (e.g., pigmentogenic programs in melanocytes). Molecular characterization and context of use are widely described in Wikipedia (Melanotan II) and review publications on the melanocortin system, including on PubMed.

Mechanism of action

Functionally MT-II is a synthetic cyclic heptapeptide, designed as an analog of α-MSH: upon activation of MC1R in melanocytes it increases cAMP and promotes eumelanin synthesis; upon activation of central MC3R/MC4R it can modulate energy balance and behavior. Receptor selectivity and dose are critical variables when interpreting in vitro/in vivo results.

Clinical and preclinical data

Scientific use

In the laboratory MT-II is used as a tool ligand for MC-receptor profiling (cAMP reporter assays), models of melanogenesis and behavioral neuropharmacology. In the clinical setting MT-II is not an approved medicinal product; studies should have clearly defined protocols, ethical approvals and pharmacovigilance (see EMA for regulatory principles).

Pharmacokinetics

When planning exposure use time points that capture early cAMP responses (minutes) and later transcriptional/pigmentary changes (hours–days). Due to the peptide nature, adsorption to plastics, proteolysis and freeze/thaw stability are relevant.

Melanotan II from MyPeptid provides conditions for reliable testing, as it is offered with purity >99% (HPLC), suitable for analytical verification, bioanalysis and method development.

Formula: C50H69N15O9

For sale only for educational and research purposes!