Epitalon 50mg – anti-aging and longevity

What is Epitalon (Epithalon)?

This peptide is used in scientific models to investigate how the organism “keeps its clock” at the cellular level and how this affects the long-term viability of tissues, without aiming for direct symptomatic action.

As a molecular class it is a synthetic tetrapeptide described as a modulator of telomerase-associated cellular programs (Telomerase/TERT–telomere dynamics axis), with reported effects on expression profiles and replicative capacity in cell systems and experimental models (Wikipedia: Epitalon; review publications in PubMed for pineal peptides/epithalamin-derivatives: PubMed).

Mechanism of action

• Experimentally considered a regulator of telomeric maintenance via changes in transcriptional programs, including TERT-associated pathways; often used to test hypotheses about cellular aging and replication.
• In in vitro designs it is applied to assess telomere length/telomerase activity, cell cycle and stress-response markers (for example qPCR/RT-qPCR panels, TRAP assay, RNA-seq).

Clinical/preclinical data

Published descriptions of Epitalon include preclinical and limited clinical reports, but many sources lack standardized numerical results (n, duration, endpoints). Personal testing by the respective researchers and laboratories is recommended.

Context of use: laboratory and clinical setting

In the laboratory Epitalon is most suitable for mechanistic experiments (cell cultures, organoids, omics profiling) and for validating markers for telomere biology. It has no regulatory approval as a medicinal product within the EMA/FDA framework; for principles of clinical evaluation and evidentiary weight refer to regulatory standards (EMA; FDA).

Pharmacokinetics (for experimental design)

Publicly available, high-quality PK parameters (bioavailability, clearance, t½) are not standardizedly established; therefore dose-time schemes should be optimized empirically, with parallel controls for stability and carriers.

Purity

Epitalon from MyPeptid provides conditions for reproducible testing, as it has a purity >99% (suitable for HPLC/LC-MS control and minimizing interference from impurities in biological readouts).

Formula

Amino acid sequence: Ala-Glu-Asp-Gly (tetrapeptide).

Formula: C14H22N4O8

Sold for educational and research use only (research-only); not intended for diagnostic, therapeutic, or veterinary use.